www.nutraceuticalsworld.com Nutraceuticals World • 51
those buying in dollars are probably getting squeezed a bit. The U.S. economy continued to get better albeit at a very slow pace. With a
newly elected Republican President and Congress, it will be interesting to see if the growth continues into economic prosperity. There
will be no excuses for gridlock.
—Dan Murray, Vice President of Business Development, Xsto Solutions, LLC
The coming year is going to provide huge growth opportunities for certain fermentable fibers that have evidence
of health benefits. Scientific data continues to show that the microbiota in the large intestines are critical to health,
and that the foods we eat can significantly change the microbiota, impacting every aspect of health and metabolism.
While an immediate focus is on digestive health and function, the bigger prize is on improved metabolism resulting
from changes in gene expression from the microbiota fermenting specific fibers.
For example, the U.S. FDA is expected to issue its ruling in 2017 on a qualified health claim petition from 2015 that
resistant starch, an insoluble fermentable fiber, helps to reduce the risk of type 2 diabetes. Numerous clinical studies
show that plant-based resistant starch significantly improves insulin sensitivity, the major biomarker for type 2 diabetes. The most
responsive groups were the ones who need it the most: people who had reduced insulin sensitivity (also called insulin resistance)
and/or classified as“prediabetic.” When this group added 15-30 grams of resistant starch/day to their diet, they saw improvements in
insulin sensitivity of 30-70%. To ask the FDA to issue this ruling, sign the Change.org petition at https://goo.gl/msmOT8.
According to the American Diabetes Association, one out of three American adults has reduced insulin sensitivity and is“predia-betic.” Without intervention, half of these 86 million Americans will develop type 2 diabetes within 10 years. Consequently, reversing
prediabetes is becoming a big business. The resistant starch-diabetes ruling promises to be significant news and strong validation that
the microbiota has a real impact on metabolism.
—Rhonda Witwer, Vice President, International Agriculture Group
The U.S. supplement market is dealing with the aftermath of scrutiny brought on by the attorneys general of New York and other
states. The industry has responded with a proposed label registration system, which has been well received by regulators. The proof of
its success will be what actually changes in the market during the next couple of years. In addition, the latest New Dietary Ingredient
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